Taste Perception and Coding in Drosophila

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Taste Perception and Coding in Drosophila

BACKGROUND Discrimination between edible and contaminated foods is crucial for the survival of animals. In Drosophila, a family of gustatory receptors (GRs) expressed in taste neurons is thought to mediate the recognition of sugars and bitter compounds, thereby controlling feeding behavior. RESULTS We have characterized in detail the expression of eight Gr genes in the labial palps, the fly's...

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Peripheral coding of bitter taste in Drosophila.

Taste receptors play a crucial role in detecting the presence of bitter compounds such as alkaloids, and help to prevent the ingestion of toxic food. In Drosophila, we show for the first time that several taste sensilla on the prothoracic legs detect bitter compounds both through the activation of specific taste neurons but also through inhibition of taste neurons activated by sugars and water....

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Taste Perception: Drosophila – A Model of Good Taste

Recent studies of taste receptors in Drosophila show remarkable parallels with the mammalian gustatory system, although the pathways are anatomically distinct. These parallels may reflect crucial constraints in the design of taste detection systems.

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The molecular basis for attractive salt-taste coding in Drosophila.

Below a certain level, table salt (NaCl) is beneficial for animals, whereas excessive salt is harmful. However, it remains unclear how low- and high-salt taste perceptions are differentially encoded. We identified a salt-taste coding mechanism in Drosophila melanogaster. Flies use distinct types of gustatory receptor neurons (GRNs) to respond to different concentrations of salt. We demonstrated...

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Breadth of tuning and taste coding in mammalian taste buds.

A longstanding question in taste research concerns taste coding and, in particular, how broadly are individual taste bud cells tuned to taste qualities (sweet, bitter, umami, salty, and sour). Taste bud cells express G-protein-coupled receptors for sweet, bitter, or umami tastes but not in combination. However, responses to multiple taste qualities have been recorded in individual taste cells. ...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2004

ISSN: 0960-9822

DOI: 10.1016/j.cub.2004.05.019